High and low level tetracycline resistance inShigella sonnei

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Ampicillin resistance of Shigella sonnei.

The ampicillin resistance of clinical isolates of Shigella sonnei is due to beta-lactamase production. Two kinds of resistance are found: low level, nontransmissible; and high level, tranmissible. The nontransmissible type of resistance results from a chromosomal mutation which increases the production of a beta-lactamase that hydrolyses cephalosporins relatively rapidly and gives cephalothin r...

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Honeybees and Tetracycline Resistance

Like animals and people, insects can serve as both collectors and disseminators of antibiotic resistance genes, as exquisitely demonstrated by a recent study (B. Tian, N. H. Fadhil, J. E. Powell, W. K. Kwong, and N. A. Moran, mBio 3[6]:e00377-12, doi:10.1128/mBio.00377-12, 2012). Notably, the relatively confined ecosystem of the honeybee gut demonstrates a large propensity for harboring a diver...

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Streptococcal tetracycline resistance mediated at the level of protein synthesis.

The mechanism of tetracycline resistance was examined in strains containing each of the three previously identified resistance determinants in Streptococcus spp. Uptake of tetracycline was measured in tetracycline-sensitive cells as well as in cells containing each of the three resistance determinants. In cells containing tetL, uptake was not observed. However, in sensitive cells and cells cont...

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Identification of tet(B), encoding high-level tetracycline resistance, in Neisseria meningitidis.

A Neisseria meningitidis strain, NIID129, with high-level resistance to tetracycline (Tet) was isolated from a Japanese woman’s nasopharynx; the MIC of tetracycline (Pfizer Pharmaceuticals Inc.) was 32 g/ml on Muller-Hinton agar (Difco) as determined by the microdilution method performed in accordance with NCCLS guidelines (6) and 24 g/ml when measured by the Etest (AB Biodisk). In order to det...

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ژورنال

عنوان ژورنال: Journal of Hygiene

سال: 1978

ISSN: 0022-1724

DOI: 10.1017/s0022172400053833